Hoxc13 Expression Pattern in Cashmere Goat Skin During Hair Follicle Development

The study investigated the expression pattern of the Hoxc13 gene in cashmere goat skin during hair follicle development. It found that the changes in Hoxc13 gene expression and skin thickness followed a similar trend during hair follicle morphogenesis. The researchers identified a 5.4 kb fragment in the Hoxc13 intron containing regulatory motifs and discovered a highly conserved region across mammals, with additional specific regions in livestock. They also examined potential pre-miRNA in this region, which could help understand the mechanisms regulating Hoxc13 gene expression.