Hot water extract of oriental melon leaf promotes hair growth and prolongs anagen hair cycle: In vivo and in vitro evaluation
April 2016
in “Food Science and Biotechnology”
TLDR Oriental melon leaf extract may help hair grow and keep it in the growing phase longer.
In 2016, a study demonstrated that hot water extracts of oriental melon leaf (OML) have a positive effect on hair growth. The in vivo study with C57BL/6 mice, using 6 mice per group, showed that OML extract shortened the telogen phase and enhanced hair growth. In vitro tests with human hair follicles, using 6 donor samples from 4 individuals, revealed that an 8-day treatment with OML extract prolonged the anagen phase and increased cell proliferation in the hair follicle bulb region. The study concluded that OML extract could be a potential therapeutic agent for hair loss prevention. For hair cycle scoring, 9 hair follicles per group were used, and for Ki-67 analysis, which measures proliferation, 6 hair follicles per group were used. Further research is recommended to identify the active components of the OML extract.
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