Hematological and hepatic effects of vascular epidermal growth factor (VEGF) used to stimulate hair growth in an animal model

    October 2013 in “BMC dermatology
    Laís Angelo Gnann, R. F. Castro, Ligia Ajaime Azzalis, David Feder, Fábio Ferreira Perazzo, Edimar Cristiano Pereira, Paulo César Pires Rosa, Virgínia Berlanga Campos Junqueira, Katya Cristina Rocha, Carlos D Aparecida Santos Machado, Francisco Camargo Paschoal, Luíz Carlos de Abreu, Vítor Engrácia Valenti, Fernando Luiz Affonso Fonseca
    TLDR VEGF gel increases hair growth but may have potential toxicity.
    The study evaluated the effects of a topical gel enriched with VEGF liposomes on hair growth and its toxicological aspects in Mesocricetus auratus. Three groups were treated with either a control gel, 1% VEGF gel, or 3% VEGF gel. After 15 days, hair density and diameter analyses showed that VEGF significantly increased hair growth and thickness compared to the control. However, biochemical and hematological analyses indicated that VEGF was not completely inert, suggesting potential toxicity. Further studies were recommended to confirm these findings.
    View this study on bmcdermatol.biomedcentral.com →

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