Normal Fur Development and Sebum Production Depend on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands

June 2011 in “ Journal of biological chemistry/The Journal of biological chemistry ”

Helena J. Maier, Marion Meixner, Dieter Hartmann, Roger Sandhoff, Lihua Wang‐Eckhardt, Inge Zöller, Volkmar Gieselmann, Matthias Eckhardt

fatty acid 2-hydroxylase FA2H sebaceous glands sebum production hair loss telogen phase hair follicle homeostasis lipids

Studysummary This study revealed that deficiency in the enzyme FA2H in mice affected sebaceous gland function, altered sebum composition, and caused cycling alopecia, highlighting FA2H's role in hair follicle homeostasis.

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