Molecular and Cellular Characterization of Avian Reticulate Scales and the Evolutionary Development of Skin Appendages in Foot Soles

July 2023 in “ Journal of developmental biology ”

Tzu-Yu Liu, Michael W. Hughes, Hao Ven Wang, Wei-Cheng Yang, Cheng‐Ming Chuong, Ping Wu

reticulate scales scutate scales Label Retaining Cell LRC regeneration stem cell niches β-keratins keratinocyte-β-keratin 13 stem cells keratin

Studysummary In this study, researchers explored the molecular and cellular traits of avian reticulate scales, finding that they lack localized stem cell niches for regeneration, unlike other scale types, leading to repair but not regeneration after wounding.

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