Development of Minoxidil-Loaded Double Emulsion PLGA Nanoparticles for the Treatment of Hair Loss

    May 2022 in “ Journal of Industrial and Engineering Chemistry ”
    Seongryeong Han, Hyung Suk Jang, Joon Hyung Shim … Heebeom Koo
    Studysummary This study observed that minoxidil-loaded nanoparticles significantly enhanced skin penetration and hair regrowth in mice within three weeks, without ethanol and propylene glycol, suggesting they are a promising delivery method for treating hair loss.
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    Research cited in this study 6

    1. Nanostructured Lipid Carriers Loaded with Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia European Journal of Pharmaceutics and Biopharmaceutics · 2022
    2. A Systematic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia Natural Products and Bioprospecting · 2020
    3. Transdermal Delivery of Minoxidil Using HA-PLGA Nanoparticles for the Treatment of Alopecia Biomaterials Research · 2019
    4. Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice International Journal of Nanomedicine · 2019
    5. Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial Journal of The American Academy of Dermatology · 2019
    6. Skin Wound Healing in Humans and Mice: Challenges in Translational Research Journal of Dermatological Science · 2017

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    3. Disorders of Hair DeckerMed Medicine · 2013
    4. Topical Minoxidil for Hair Growth in Alopecia Areata and Androgenetica Drugs · 1987
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