Finasteride in the Treatment of Androgenetic Alopecia

    April 2004 in “ Expert Opinion on Pharmacotherapy ”
    James F. Libecco, Wilma F. Bergfeld
    Studysummary This article reviews the use of finasteride for treating male pattern hair loss, highlighting its mechanism of action in reducing DHT and noting its safety profile with some common adverse effects.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 20

    1. Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2002
    2. Female Pattern Hair Loss Clinical and Experimental Dermatology · 2002
    3. Unilateral Gynecomastia Induced by Treatment with 1 mg of Oral Finasteride Archives of Dermatology · 2002
    4. Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2000
    5. Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia British Journal of Dermatology · 2000
    6. Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss Journal of The American Academy of Dermatology · 1999
    7. Finasteride Is the Main Inhibitor of 5α-Reductase Activity in Microdissected Dermal Papillae of Human Hair Follicles Archives of Dermatological Research · 1999
    8. Finasteride Drugs · 1999
    9. A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride Clinical Pharmacology & Therapeutics · 1998
    10. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    11. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998
    12. Comparison of Finasteride Versus Spironolactone in the Treatment of Idiopathic Hirsutism Fertility and Sterility · 1997
    13. Reversible Severe Myopathy During Treatment with Finasteride Muscle & Nerve · 1997
    14. Effects of Finasteride, a Type 2 5-Alpha Reductase Inhibitor, on Fetal Development in the Rhesus Monkey (Macaca Mulatta) Teratology · 1997
    15. Treatment of Hirsutism by Finasteride and Flutamide in Women with Polycystic Ovary Syndrome Gynecological Endocrinology · 1997
    16. Guidelines of Care for Androgenetic Alopecia Journal of The American Academy of Dermatology · 1996
    17. Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives Fertility and Sterility · 1996
    18. Clinical Pharmacokinetics and Pharmacodynamics of Finasteride Clinical Pharmacokinectics · 1996
    19. Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine The Journal of Clinical Pharmacology · 1993
    20. Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers The Journal of Clinical Endocrinology and Metabolism · 1990

    Related research 8

    1. The Impact of 5α-Reductase Inhibitor Use for Male Pattern Hair Loss on Men's Health Current Urology Reports · 2018
    2. Sexual Side Effects of 5-Alpha-Reductase Inhibitors Finasteride and Dutasteride: A Comprehensive Review Dermatology Online Journal · 2017
    3. Adverse Effects and Safety of 5-Alpha Reductase Inhibitors (Finasteride, Dutasteride): A Systematic Review PubMed · 2016
    4. Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride American Journal of Men's Health · 2014
    5. Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients The Journal of Sexual Medicine · 2010
    6. Finasteride in the Treatment of Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2004
    7. Therapy of Androgenetic Alopecia with Finasteride: What Must Be Considered in Consultation and Drug Prescribing PubMed · 1999
    8. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992