How to Explain the Beneficial Effects of Platelet-Rich Plasma

April 2024 in “ Periodontology 2000 ”

Reinhard Gruber

platelet-rich plasma PRP growth factors autologous blood platelets leukocytes

TLDR Platelet-rich plasma may help healing due to growth factors from platelets.

This review discusses the use of platelet-rich plasma (PRP), a component of autologous blood containing platelets and leukocytes, which is commonly used in sports medicine, orthopedics, and dermatology despite limited evidence in dentistry. The beneficial effects of PRP are often linked to growth factors released from platelets, though this evidence is indirect. The review aims to revisit PRP by summarizing preparation protocols, examining its cellular and molecular composition, and exploring its potential benefits at the cellular and molecular levels, with a focus on its applications in various medical fields.

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Research cited in this study

7 / 7 results

research Efficacy of Platelet-Rich Plasma Therapy in Oral Lichen Planus: A Systematic Review

26 citations , April 2023 in “Medicina”

Platelet-rich plasma therapy improves oral lichen planus symptoms with few side effects.

research Use of Activated Platelet-Rich Plasma on Alopecia: A Systematic Review and Meta-Analysis

March 2023 in “Aesthetic Surgery Journal”

Activated platelet-rich plasma is effective and safe for treating hair loss.

research Study of Platelet-Rich Plasma Application for Skin and Plastic Surgery in Recent 20 Years: A Bibliometric Analysis

1 citations , February 2023 in “Journal of cosmetic dermatology”

PRP use in skin care and plastic surgery is growing, especially in the U.S. and Italy.

research An Umbrella Review of the Use of Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia

January 2023 in “Journal of Cosmetic Dermatology”

PRP is effective for treating hair loss, improving hair density, count, and thickness.

research Autologous Platelet-Rich Plasma Treatment for Androgenic Alopecia: A Systematic Review and Meta-Analysis of Clinical Trials on Patient Safety, Efficacy and Outcomes

December 2022 in “Plastic and Reconstructive Surgery”

PRP is an effective and safe treatment for hair loss.

research A Comprehensive Review of Platelet-Rich Plasma for the Treatment of Dermatologic Disorders

1 citations , November 2022 in “Journal of Dermatological Treatment”

Platelet-rich plasma can increase hair density and may help treat some skin conditions, but it's costly, not FDA-approved, and needs more research.

research Platelet-Rich Plasma: A Promising Regenerative Therapy in Gynecological Disorders

3 citations , September 2022 in “Cureus”

Platelet-rich plasma shows promise for treating various female reproductive health issues but requires more research.

Similar Research

6 / 1000+ results

research Platelet-Rich Plasma: Molecular Mechanisms, Actions, and Clinical Applications in the Human Body

November 2025 in “International Journal of Molecular Sciences”

PRP shows promise in healing and regeneration but needs standardized protocols for consistent results.

research Platelet-Rich Plasma in Dermatology: New Insights on the Cellular Mechanism of Skin Repair and Regeneration

1 citations , December 2023 in “Life”

PRP helps skin heal, possibly through special cells called telocytes.

Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Regrowth in Androgenetic Alopecia: Biomolecular Pathway Analysis and Clinical Evaluation

research Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Regrowth in Androgenetic Alopecia: Biomolecular Pathway Analysis and Clinical Evaluation

69 citations , April 2019 in “Biomedicines”

PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.

Dermapen Treatments for Healing Pockmarked Skin in Male Wistar Rats (Rattus Norvegicus): A Study Comparing Platelet-Rich Plasma with Salmon DNA Serum

research Dermapen Treatments for Healing Pockmarked Skin in Male Wistar Rats (Rattus Norvegicus): A Study Comparing Platelet-Rich Plasma with Salmon DNA Serum

December 2023 in “Jurnal Penelitian Pendidikan IPA”

PRP heals pockmarked skin better than salmon DNA serum.

research Platelet-Rich Plasma in Dermatology and Aesthetic Medicine

August 2024 in “Quality in Sport”

PRP helps with skin, hair, and wound treatments but needs more research for standard use.

research Platelet-Rich Plasma in Cosmetic Surgery

5 citations , January 2013 in “Otorhinolaryngology clinics : an international journal”

Platelet-rich plasma may improve healing and hair growth in cosmetic surgery but results vary.

How to Explain the Beneficial Effects of Platelet-Rich Plasma

Research cited in this study

research Efficacy of Platelet-Rich Plasma Therapy in Oral Lichen Planus: A Systematic Review

research Use of Activated Platelet-Rich Plasma on Alopecia: A Systematic Review and Meta-Analysis

research Study of Platelet-Rich Plasma Application for Skin and Plastic Surgery in Recent 20 Years: A Bibliometric Analysis

research An Umbrella Review of the Use of Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia

research Autologous Platelet-Rich Plasma Treatment for Androgenic Alopecia: A Systematic Review and Meta-Analysis of Clinical Trials on Patient Safety, Efficacy and Outcomes

research A Comprehensive Review of Platelet-Rich Plasma for the Treatment of Dermatologic Disorders

research Platelet-Rich Plasma: A Promising Regenerative Therapy in Gynecological Disorders

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