Early Onset Androgenetic Alopecia in Men and Associated Risk Factors: A Hospital-Based Study

    May 2017 in “ International Journal of Research in Dermatology ”
    Thansiha Nargis, Vishal Bejai, Malcolm Pinto, Manjunath Mala Shenoy
    TLDR Early onset hair loss in young men is common and linked to family history and alcohol use.
    The study investigated early onset androgenetic alopecia (AGA) in men and its associated risk factors, involving 103 male patients over 18 years old. It found that 68% of participants were aged 21-30, and a significant association was observed between early AGA onset and alcohol consumption (73.3%). Familial AGA was prevalent in 68% of cases, with paternal inheritance (62.8%) being more common than maternal (8.6%). Systemic diseases were present in 12.6% of patients, with hypertension being the most common. The study concluded that early onset AGA is common in younger men, often causing anxiety, and emphasized the importance of early management, especially in those with a family history. Environmental factors like smoking and alcohol were considered potential contributors to AGA.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 7 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  65 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 2 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community C’est terrible - at my wits end

      in Female  443 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Fuck hair loss; acquire beard.

      in Shaved/buzzed  933 upvotes 2 years ago
      A user's transformation from an accountant to a spartan with a full beard, discussing the potential of DUPA and alopecia areata, as well as treatments like vitamins, topicals, and natural treatments for potential regrowth.

    Related Research

    13 / 13 results