Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double Blind, Placebo-Controlled Trial1
January 2000
in “The Journal of Clinical Endocrinology and Metabolism”
TLDR Spironolactone most effective for hirsutism, but has side effects.
This study compared the effectiveness of spironolactone, flutamide, finasteride, and a placebo in treating hirsutism in women. Spironolactone and flutamide were found to be more effective than finasteride and placebo in reducing hirsutism, but spironolactone had more side effects. The study involved 40-134 women and lasted for 6 months. Overall, spironolactone was found to be the most effective treatment for hirsutism, but its side effects should be considered.
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