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    Real-World Evidence for Baricitinib in the Treatment of Atopic Dermatitis and Alopecia Areata: Systematic Literature Review 2020–2023

    May 2025 in “ Dermatology and Therapy ”
    Julien Sénéschal, Lgnasi Figueras Nart, Silvia Sabatino … Αναστασία Λαμπροπούλου
    Studysummary This study found that baricitinib improved symptoms of atopic dermatitis and alopecia areata in both adults and children in real-world settings, aligning with clinical trial results, while noting low discontinuation due to adverse events and no new safety concerns.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 21

    1. European Expert Consensus Statement on the Systemic Treatment of Alopecia Areata JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2024
    2. Effectiveness and Safety of Baricitinib in Patients With Severe Alopecia Areata: A 36-Week Multicenter Real-World Experience Journal of Dermatological Treatment · 2023
    3. Dupilumab Therapy for Alopecia Areata in a 4-Year-Old Patient Resistant to Baricitinib Frontiers in Medicine · 2023
    4. Real-Life Effectiveness and Tolerance of Baricitinib for the Treatment of Severe Alopecia Areata with 1-Year Follow-Up Data Dermatology and Therapy · 2023
    5. Early Real-World Experience With Baricitinib in the Treatment of Severe Alopecia Areata Journal of The American Academy of Dermatology · 2023
    6. Combination of Baricitinib and Conventional Immunomodulating Therapy for Alopecia Totalis Skin Research and Technology · 2023
    7. Major Improvement of Very Severe Alopecia Areata in Patients Treated With the Combination of Baricitinib and Low Doses of Corticosteroids: An Eight-Case Series Clinical and Experimental Dermatology · 2023
    8. Efficacy and Safety of Baricitinib in Managing Severe Alopecia Areata: A 6-Month Real-World Experience British Journal of Dermatology · 2023
    9. Baricitinib for the Treatment of Alopecia Areata Drugs · 2023
    10. Treatment of Moderate-to-Severe Alopecia Areata in Pre-Adolescent Children with Baricitinib British Journal of Dermatology · 2023
    11. Switching Between Tofacitinib and Baricitinib in Alopecia Areata: A Review of Clinical Response Journal of the American Academy of Dermatology · 2023
    12. Trends in Prevalence and Incidence of Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Among Adults and Children in a US Employer-Sponsored Insured Population JAMA Dermatology · 2023
    13. Atopic Dermatitis And Multilocular Alopecia Areata Simultaneously Treated With Baricitinib Actas Dermo-Sifiliográficas · 2023
    14. Treatment of Moderate-to-Severe Alopecia Areata in Adolescents With Baricitinib: A Retrospective Review of 29 Patients Journal of The American Academy of Dermatology · 2023
    15. Integrated Safety Analysis of Baricitinib in Adults With Severe Alopecia Areata From Two Randomized Clinical Trials British journal of dermatology/British journal of dermatology, Supplement · 2022
    16. The Burden of Disease in Alopecia Areata: Canadian Online Survey of Patients and Caregivers JMIR dermatology · 2022
    17. Efficacy and Safety of Baricitinib in Patients With Refractory Alopecia Areata Dermatologic Therapy · 2022
    18. Two Phase 3 Trials of Baricitinib for Alopecia Areata The New England Journal of Medicine · 2022
    19. The Associated Burden of Mental Health Conditions in Alopecia Areata: A Population-Based Study in UK Primary Care British Journal of Dermatology · 2022
    20. Efficacy and Safety of the Oral Janus Kinase Inhibitor Baricitinib in the Treatment of Adults with Alopecia Areata: Phase 2 Results from a Randomized Controlled Study Journal of The American Academy of Dermatology · 2021
    21. Complete Regrowth of Beard Hair with Ruxolitinib in an Alopecia Universalis Patient Skin appendage disorders · 2017

    Related research 1

    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019