Baldness And The Androgen Receptor: The AR Polyglycine Repeat Polymorphism Does Not Confer Susceptibility To Androgenetic Alopecia

    January 2007 in “ Human Genetics ”
    Justine A. Ellis, Katrina J Scurrah, J Cobb … Stephen B. Harrap
    Studysummary In this study, researchers found that while the SNP rs6152 is strongly associated with androgenetic alopecia, the GGN triplet repeat is not, suggesting the causative variant is likely a non-coding one.
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    Research cited in this study 7

    1. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005
    2. The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia Cancer Epidemiology, Biomarkers & Prevention · 2005
    3. Validity of Self-Reported Male Balding Patterns in Epidemiological Studies BMC Public Health · 2004
    4. Genetic Basis of Male Pattern Baldness Journal of Investigative Dermatology · 2003
    5. Polymorphism of the Androgen Receptor Gene Is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001
    6. Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes Journal of Investigative Dermatology · 1998
    7. The Inheritance Of Common Baldness: To Be Or Not To Be? Journal of the American Academy of Dermatology · 1984