Efficacy and Safety of Long-Term Azathioprine Therapy for Severe Alopecia Areata: A 10-Year Cohort Study

This 10-year cohort study evaluated the long-term efficacy and safety of azathioprine as a systemic monotherapy for moderate to severe alopecia areata in 63 patients. The study found that azathioprine significantly improved hair regrowth, with a mean percentage of hair regrowth of 92.69% and a reduction in mean hair loss from 74.2% before treatment to 5.2% after 10 years. The mean hair loss score also improved significantly, indicating that azathioprine is a safe and effective treatment for severe alopecia areata.