Abrocitinib Treatment in Diffuse Alopecia Areata: A Case Report and Literature Review

    August 2026 in “ Clinical Case Reports ”
    X. J. Zhang, JianBo Zhong, Liming Wu … YunMi Qiu
    Studysummary In this case report, a patient with diffuse alopecia areata experienced complete hair regrowth after treatment with oral abrocitinib, with no adverse effects observed.
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    Research cited in this study 11

    1. Successful Treatment of Severe Diffuse Alopecia Areata with Abrocitinib Anais Brasileiros de Dermatologia · 2025
    2. Real-World Effectiveness and Safety of Janus Kinase Inhibitors in Alopecia Areata: A Retrospective Cohort Study of 72 Patients Acta Dermato Venereologica · 2025
    3. Off-Label Uses of Abrocitinib: Review of Emerging Therapeutic Applications Beyond Atopic Dermatitis Life · 2024
    4. Successful Treatment of Alopecia Universalis With Abrocitinib: A Case Report Journal of Dermatological Treatment · 2023
    5. Effective Treatment of Refractory Alopecia Areata in Pediatric Patients With Oral Abrocitinib Journal of cosmetic dermatology · 2023
    6. Alopecia Areata: An Updated Review for 2023 Journal of Cutaneous Medicine and Surgery · 2023
    7. Alopecia Areata: Burden of Disease, Approach to Treatment, and Current Unmet Needs Clinical, Cosmetic and Investigational Dermatology · 2023
    8. An Overview of JAK/STAT Pathways and JAK Inhibition in Alopecia Areata Frontiers in immunology · 2022
    9. A Case of Atopic Dermatitis with Alopecia Universalis in a Patient Treated with Abrocitinib JAAD case reports · 2022
    10. Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2017
    11. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014