A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism

    Stefano Venturoli, Ombretta Marescalchi, Fabio Colombo, S. Macrelli, B. Ravaioli, A. Bagnoli, Roberto Paradisi, Carlo Flamigni
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    TLDR Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.
    This document summarizes various studies that compared different drug regimens for treating hirsutism in women. The studies found that low dose flutamide, finasteride, and cyproterone acetate-estrogen were effective in reducing hair growth, while ketoconazole had negative side effects. Cyproterone acetate-estrogen was found to be the most effective treatment option in most studies, but had some side effects. Flutamide was also effective, but had more side effects than other treatments. Finasteride was effective with minimal side effects. Overall, the studies suggest that different drug regimens can be effective in treating hirsutism, but the choice of treatment should be based on individual patient characteristics and potential side effects.
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