Transcriptome Analyses of Reprogrammed Feather/Scale Chimeric Explants Revealed Co-Expressed Epithelial Gene Networks During Organ Specification

October 2018 in “ BMC genomics ”

Yung-Chih Lai, Ya-Chen Liang, Ting‐Xin Jiang, Randall B. Widelitz, Ping Wu, Cheng‐Ming Chuong

β-catenin retinoic acid epidermal fate dermal fate chromatin open sites transcriptome analyses gene networks skin appendage phenotypes beta-catenin RA skin cell fate open chromatin sites gene expression analysis skin features

Studysummary This study reveals that β-catenin and retinoic acid are key regulators in the gene networks controlling the fate of skin appendages, such as scales and feathers.

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