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    GlossaryDermal White Adipose Tissue (dermal fat)

    layer of fat in the skin's dermis aiding hair growth

    Dermal White Adipose Tissue (DWAT) is a layer of fat located within the skin, specifically in the dermis. It plays a crucial role in skin homeostasis, providing insulation, energy storage, and contributing to the skin's structural integrity. DWAT is also involved in hair follicle cycling and wound healing, making it an important area of study for both dermatology and metabolic research.

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      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn Redensyl

      commercial product with a blend of mostly natural ingredients for hair regrowth

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community 6 months on Min 4 months on fin update

      in Progress Pictures  439 upvotes 7 months ago
      A user shared a 6-month update on hair regrowth using Minoxidil 5% liquid twice daily and Finasteride 1mg once daily, along with weekly use of a 1mm Derma roller for 5 weeks. They are pleased with the fuller hair and plan to continue Minoxidil but may temporarily stop Finasteride when trying for a baby.

      community Very reluctantly starting Finasteride.

      in Finasteride/Dutasteride  84 upvotes 8 months ago
      A 23-year-old started taking 0.25 mg of Finasteride daily for hair loss after trying Minoxidil and derma rolling without success. People shared varied experiences with Finasteride, discussing potential side effects, effectiveness, and personal decisions regarding hair loss treatment.

      community 8 years of Finasteride and Minoxidil (includes a photo)

      in Update  71 upvotes 1 year ago
      User has used Finasteride, Minoxidil, and derma roller for 8 years to treat hair loss but is still losing the battle. Others suggest trying Dutasteride, oral Minoxidil, RU58841, or considering a hair transplant.