The 5α-Reductase Inhibitor Finasteride Is Not Associated With Alterations in Sleep Spindles in Men Referred for Polysomnography

    October 2015 in “ Human Psychopharmacology-clinical and Experimental ”
    Michael G. Goldstein, Jesse D Cook, David T. Plante
    Studysummary In this study, finasteride was found not to be associated with changes in sleep spindle activity or morphology in men undergoing sleep studies.
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    Research cited in this study 8

    1. Patients Treated for Male Pattern Hair Loss with Finasteride Show Altered Levels of Neuroactive Steroids in Cerebrospinal Fluid and Plasma After Discontinuation The Journal of Steroid Biochemistry and Molecular Biology · 2014
    2. 5α-Reductases in Human Physiology: An Unfolding Story Endocrine Practice · 2012
    3. Novel Modulatory Effects of Neurosteroids and Benzodiazepines on Excitatory and Inhibitory Neurons Excitability: A Multi-Electrode Array Recording Study Frontiers in Neural Circuits · 2012
    4. Finasteride Induced Depression: A Prospective Study BMC clinical pharmacology · 2006
    5. A New Look at the 5-Alpha-Reductase Inhibitor Finasteride Cns Drug Reviews · 2006
    6. Depression Related to Finasteride Administration for Androgenetic Alopecia Journal of Dermatology · 2002
    7. Steroid 5α-Reductases and 3α-Hydroxysteroid Dehydrogenases: Key Enzymes in Androgen Metabolism Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism · 2001
    8. Inhibition of Steroid 5 Alpha-Reductase with Finasteride: Sleep-Related Erections, Potency, and Libido in Healthy Men The Journal of Clinical Endocrinology and Metabolism · 1995