Single Cell Deciphering of Pruritic Keloids: The Interaction Between Fibroblasts and Schwann Cells Through the Midkine Signaling

January 2025 in “ Burns & Trauma ”

En Yang, Ruoqing Xu, Liying Tu, Hanrui Zhang, Shenying Luo, Hsin Liang, Yunhan Liu, Shuchen Gu, Yixuan Zhao, Xin Huang, Tao Zan

fibroblasts Schwann cells keloids Midkine neurogenesis substance P neuropeptide scRNA-seq axonogenesis

Studysummary This study found that targeting the molecule Midkine may reduce pain and itching in keloid patients by inhibiting specific Schwann cell activities contributing to these symptoms.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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