Sostdc1 Defines the Size and Number of Skin Appendage Placodes

February 2012 in “ Developmental biology ”

Katja Maria Närhi, Mark Tümmers, Laura Ahtiainen, Nobuyuki Itoh, Irma Thesleff, Marja L. Mikkola

Sostdc1 hair follicles vibrissae hair placodes Wnt/β-catenin signaling mammary glands nipple epidermis whiskers hair buds Wnt signaling

Studysummary This study found that the absence of Sostdc1 in mice alters mammary gland and hair follicle development, particularly by increasing vibrissae numbers and causing unusual nipple-like structures.

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