Phylogeny of the Hair Follicle: The Sebogenic Hypothesis

    December 2007 in “ Journal of Investigative Dermatology ”
    Kurt S. Stenn, Yujie Zheng, Satish Parimoo
    Studysummary This study proposes the sebogenic hypothesis, suggesting that hair follicles evolved from primitive sebaceous glands to facilitate lipid transport and improve water retention in early land-dwelling animals.
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    Research cited in this study 5

    1. Smad7-Induced Beta-Catenin Degradation Alters Epidermal Appendage Development Developmental Cell · 2006
    2. Report From The Cicatricial Alopecia Colloquium Journal of Investigative Dermatology · 2006
    3. Defolliculated (Dfl): A Dominant Mouse Mutation Leading to Poor Sebaceous Gland Differentiation and Total Elimination of Pelage Follicles Journal of Investigative Dermatology · 2002
    4. Tcf3 and Lef1 Regulate Lineage Differentiation of Multipotent Stem Cells in Skin Genes & Development · 2001
    5. Asebia-2J (Scd1ab2J): A New Allele and a Model for Scarring Alopecia ˜The œAmerican journal of pathology · 2000

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