Impact of Stem Cells on Reparative Regeneration in Abdominal and Dorsal Skin in the Rat

    January 2024 in “ Journal of developmental biology ”
    Evgeniya Kananykhina, Andrey Elchaninov, G. B. Bol’shakova
    Studysummary In this study, researchers observed that abdominal wounds in laboratory rats healed faster, completing epithelialization in 20 days versus 30 days for back wounds, possibly due to a higher expression of skin stem cell marker genes in the abdominal area.
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    Research cited in this study 8

    1. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations During Wound Healing Cell Reports · 2018
    2. Defining Stem Cell Dynamics and Migration During Wound Healing in Mouse Skin Epidermis Nature Communications · 2017
    3. Hair Follicle and Interfollicular Epidermal Stem Cells Make Varying Contributions to Wound Regeneration Cell Cycle · 2015
    4. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015
    5. Epithelial Stem Cells And Implications For Wound Repair Seminars in Cell & Developmental Biology · 2012
    6. Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells Cell stem cell · 2011
    7. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    8. An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007