Topical Niacinamide Does Not Stimulate Hair Growth Based on the Existing Body of Evidence

    January 2020 in “ International Journal of Cosmetic Science ”
    John E. Oblong, A. W. Peplow, Scott M. Hartman, Michael Davis
    Studysummary In this in vitro study, niacinamide was found not to stimulate VEGF synthesis across a wide range of doses.
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    Research cited in this study 5

    1. Topical Adenosine Increases Thick Hair Ratio in Japanese Men with Androgenetic Alopecia International Journal of Cosmetic Science · 2015
    2. A Pilot Study Evaluating the Efficacy of Topically Applied Niacin Derivatives for Treatment of Female Pattern Alopecia Journal of Cosmetic Dermatology · 2005
    3. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    4. Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil Journal of Investigative Dermatology · 2001
    5. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998