A Novel Monoclonal Antibody to the Outer Root Sheath Cells

    October 1994 in “ Journal of Dermatological Science ”
    Nazuko Tatsuta, Tadashi Tezuka
    Studysummary This study developed a novel monoclonal antibody, TYHF-1, which specifically reacts with hair keratins but not with epidermal keratins or various other tissue cells.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jdsjournal.com →
    Discuss this study in the Community →

    Research cited in this study 6

    1. Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1991
    2. Expression of Hair-Related Keratins in a Soft Epithelium: Subpopulations of Human and Mouse Dorsal Tongue Keratinocytes Express Keratin Markers for Hair, Skin, and Esophageal Types of Differentiation Experimental Cell Research · 1989
    3. Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    4. Cell Differentiation in Human Anagen Hair and Hair Follicles Studied with Anti-Hair Keratin Monoclonal Antibodies Journal of Investigative Dermatology · 1986
    5. Immunological Characteristics and Histological Distribution of Human Hair Fibrous Proteins Studied with Anti-Hair Keratin Monoclonal Antibodies HKN-2, HKN-4, and HKN-6 Journal of Histochemistry & Cytochemistry · 1986
    6. Different Keratin Polypeptides in Epidermis and Other Epithelia of Human Skin: A Specific Cytokeratin of Molecular Weight 46,000 in Epithelia of the Pilosebaceous Tract and Basal Cell Epitheliomas The Journal of Cell Biology · 1982

    Related research 6

    1. Functional Analysis of Keratin Components in the Mouse Hair Follicle Inner Root Sheath British Journal of Dermatology · 2004
    2. Study on the Distribution of Hair Keratin in Normal Hair Follicles by Immunohistochemical Staining Acta Academiae Medicine Militaris Tertiae · 2000
    3. Solid Basal Cell Epithelioma Possibly Originates From the Outer Root Sheath of the Hair Follicle PubMed · 1993
    4. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989
    5. Keratins of the Human Hair Follicle: Hyperproliferative Keratins Consistently Expressed in Outer Root Sheath Cells In Vivo and In Vitro Differentiation · 1987
    6. Immunohistochemical Staining Characteristics of Epidermal Appendages: Hair Follicles and Eccrine Sweat Glands to Anti-Epidermal Keratin Antisera Acta Dermato Venereologica · 1984