Flavonoids as Potential Wound-Healing Molecules: Emphasis on Pathways Perspective

February 2023 in “ International Journal of Molecular Sciences ”

Nabilah Zulkefli, Che Nur Mazadillina Che Zahari, Nor Hafiza Sayuti, Ammar Akram Kamarudin, Norazalina Saad, Hamizah Shahirah Hamezah, Hamidun Bunawan, Syarul Nataqain Baharum, Ahmed Mediani, Qamar Uddin Ahmed, Ahmad Fahmi Harun Ismail, Murni Nazira Sarian

flavonoids quercetin Wnt/β-catenin TGF-β NF-κB pro-collagen antioxidant anti-inflammatory

Studysummary This review compiled evidence suggesting that flavonoids may promote skin wound healing due to their anti-inflammatory, angiogenesis, re-epithelialization, and antioxidant properties, while also discussing current limitations and future prospects for these compounds as wound-healing agents.

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