Hierarchically Assembled Nanofiber Scaffolds With Dual Growth Factor Gradients Promote Skin Wound Healing Through Rapid Cell Recruitment
February 2024
in “
Advanced Science
”
nanofiber scaffold growth factor gradients EGF VEGF extracellular matrix cell proliferation cell migration tissue regeneration wound closure scar formation hair follicle regeneration RNAseq Bioinformatics Analysis Histological Observations Immunohistochemical Staining epidermal growth factor vascular endothelial growth factor
Studysummary This study highlights that a novel radially aligned nanofiber scaffold with dual growth factor gradients significantly enhances wound healing, promoting cell migration, epidermal regeneration, and angiogenesis, ultimately leading to improved wound closure, immune regulation, and tissue remodeling compared to other groups.
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