Integrated Single-Cell Chromatin and Transcriptomic Analyses of Human Scalp Reveal Etiological Insights Into Genetic Risk for Hair and Skin Disease
September 2022
in “
bioRxiv (Cold Spring Harbor Laboratory)
”
single-cell RNA sequencing ATAC sequencing gene-regulatory networks hair follicle niche enhancer-gene links androgenetic alopecia dermal papilla cells open chromatin regions SNPs transcription factor binding motifs WNT10A IL18RAP single-cell RNA seq ATAC seq gene networks hair follicle enhancer links AGA dermal papilla chromatin regions single nucleotide polymorphisms transcription factor motifs
Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.
Studysummary This study identifies gene-regulatory networks related to genetic variants in skin and hair diseases, suggesting that dermal papilla cells are crucial in androgenetic alopecia.
Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
