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technique identifies open chromatin regions to study gene regulation

ATAC-seq, or Assay for Transposase-Accessible Chromatin using sequencing, is a technique used to study the accessibility of chromatin, which is the material that makes up chromosomes. By identifying regions of DNA that are open and accessible, ATAC-seq helps researchers understand which parts of the genome are active and potentially involved in gene regulation. This method is valuable for studying gene expression patterns in various biological contexts, including development, disease, and cellular responses.

Related Terms

• ChIP-seq
• DNase-seq
• FAIRE-seq