17β-Estradiol Increases APE1/Ref-1 Secretion in Vascular Endothelial Cells and Ovariectomized Mice: Involvement of Calcium-Dependent Exosome Pathway

    August 2021 in “ Biomedicines ”
    Yu‐Ran Lee, Hee-Kyoung Joo, Eun‐Ok Lee … Byeong Hwa Jeon
    Studysummary This study found that 17β-estradiol was the most powerful hormone for inducing APE1/Ref-1 secretion in cultured vascular endothelial cells, with secretion occurring through exosomes dependent on estrogen receptors and intracellular calcium.
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    Research cited in this study 1

    1. Assessment of the Usefulness of Dihydrotestosterone in the Diagnostics of Patients with Androgenetic Alopecia Postepy Dermatologii I Alergologii · 2014