Androgen Receptor Gene Polymorphisms and Risk for Androgenetic Alopecia: A Meta-Analysis

October 2011 in “ Clinical and Experimental Dermatology ”

F. L. Zhuo, Wei Xu, Lin Wang, Yanwen Wu, Z. Z. Xu, Jingzhou Zhao

androgen receptor gene polymorphisms androgenetic alopecia AGA G allele AR Stul polymorphism CAG triplet-repeat polymorphism GGC triplet-repeat polymorphism androgen receptor genetic variations male pattern baldness

Studysummary This meta-analysis suggests that the G allele of AR StuI polymorphism might be a potential risk factor for AGA, particularly in white populations.

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research Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities

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In this study, no association was found between the AR gene and type II androgenetic alopecia in Egyptian women, suggesting it is not a useful biomarker for predisposition.

research Prevalence and Types of Androgenetic Alopecia in Shanghai, China: A Community-Based Study

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research EDA2R Is Associated With Androgenetic Alopecia

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research Association of Androgenetic Alopecia With Smoking and Its Prevalence Among Asian Men

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In this study, smoking status and intensity were significantly associated with moderate or severe androgenetic alopecia among Asian men, after accounting for age and family history.

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research Baldness And The Androgen Receptor: The AR Polyglycine Repeat Polymorphism Does Not Confer Susceptibility To Androgenetic Alopecia

60 citations , January 2007 in “Human Genetics”

In this study, researchers found that while the SNP rs6152 is strongly associated with androgenetic alopecia, the GGN triplet repeat is not, suggesting the causative variant is likely a non-coding one.

research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia

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Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia

research The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia

76 citations , April 2005 in “Cancer Epidemiology, Biomarkers & Prevention”

This study found that the AR-E211 A allele is associated with a lower risk of both metastatic prostate cancer and androgenetic alopecia in an Australian population.

research Genetic Basis of Male Pattern Baldness

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research Molecular Mechanisms of Androgenetic Alopecia

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This paper discusses key mechanisms of androgen metabolism in androgenetic alopecia and reports the effectiveness of treatments like oral finasteride and topical minoxidil, highlighting the limited success rate due to factors like follicular inflammation.

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