Perforin Expression by Cutaneous Gamma Delta T Cells

August 2020 in “ Frontiers in Immunology ”

Katelyn O’Neill, Irena Pastar, Marjana Tomić-Canić, Nataša Štrbo

gamma delta T cells Perforin Perforin-2 skin inflammation wound healing antimicrobial defense tumor elimination virally infected cells autoimmune diseases psoriasis IL-17 IL-22 skin immunity GD T cells immune defense skin health

Studysummary This review explores the expression of Perforin by gamma delta T cells in human skin and its role in cytotoxicity but reports no new experimental results.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on frontiersin.org →

Discuss this study in the Community →

Research cited in this study

2 / 2 results

research Human αβ and γδ T Cells in Skin Immunity and Disease

83 citations , June 2018 in “Frontiers in immunology”

This review discusses the roles of αβ and γδ T cells in skin health and disease and reports no new clinical results; the authors highlight potential therapeutic developments.

research Fgf9 From Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding

237 citations , June 2013 in “Nature Medicine”

This study found that fibroblast growth factor 9, initially secreted by γδ T cells, plays a key role in modulating hair follicle regeneration in mice after skin wounds.