Low topical fin + 0.5% pyrilutamide
    2/24/2026

    From the encyclopedia
    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    Pyrilutamide →

    highly targeted anti-androgen that might have minimal systemic effects

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 Finasteride (topical) 0.025% 1x daily
    💧 Pyrilutamide (topical) 0.5% 1x daily
    the tone is 😐 neutral.

    Other terms

    Using a combination of low-dose topical finasteride (0.025%) and 0.5% pyrilutamide for hair loss, with a focus on minimizing side effects. The user seeks experiences and results from others who have tried this combination.
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    5 / 5 results

      community For people with overly oily hair, does topical finasteride/dutasteride/antiandrogens (like RU or Pyrilutamide) reduce sebum overproduction?

      in Finasteride/Dutasteride  6 upvotes 3 years ago
      The conversation discusses whether topical finasteride, dutasteride, or antiandrogens like RU58841 can reduce sebum overproduction as an early indicator of their effectiveness in treating hair loss. It suggests that while hair growth may take months to observe, a decrease in oiliness could be a quicker sign of a product's action.

      community Pyrilutamide vs Topical Finasteride

       4 upvotes 10 months ago
      Topical finasteride is currently more effective than pyrilutamide for hair loss. Combining treatments like topical finasteride and pyrilutamide may enhance results due to different mechanisms.

      community Pyrilutamide vs topical finasteride

       2 upvotes 1 year ago
      The user is considering switching to topical finasteride or pyrilutamide to stabilize hair loss before a hair transplant, currently using oral minoxidil and finasteride. Suggestions include sticking to the current regimen as it is already potent, and caution against using pyrilutamide from unreliable sources.

      community Breezula / pyrilutamide vs topical fin / dut for added protection on TRT?

       2 upvotes 5 months ago
      A 35-year-old is considering Breezula, Pyrilutamide, or topical finasteride/dutasteride to protect against hair loss while on testosterone replacement therapy (TRT). They currently use finasteride, oral minoxidil, and dutasteride but experienced increased hair shedding with TRT.

      community Pyrilutamide and Topical Fin/Min

      in Basic Questions  48 upvotes 2 months ago
      Pyrilutamide should be applied before topical minoxidil and finasteride, allowing time between applications to prevent degradation from water. Users discuss the order and timing of applying these treatments for hair loss.

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    6 / 6 results