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Glossary Vitamin D Receptor

protein that binds vitamin D to regulate gene expression

The Vitamin D Receptor (VDR) is a protein found in various cells throughout the body that binds to vitamin D, allowing it to regulate the expression of specific genes. This receptor plays a crucial role in maintaining calcium and phosphate balance, which is essential for healthy bone formation, and it also influences immune system function and hair follicle cycling.

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Research

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research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

1533 citations , October 2008 in “Endocrine reviews”

This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.

research The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed

1308 citations , March 1998 in “Journal of bone and mineral research”

This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.

research Normalization of Mineral Ion Homeostasis by Dietary Means Prevents Hyperparathyroidism, Rickets, and Osteomalacia, But Not Alopecia in Vitamin D Receptor-Ablated Mice¹

519 citations , October 1998 in “Endocrinology”

The study found that normalizing mineral ion levels in vitamin D receptor-ablated mice prevented hyperparathyroidism and bone disorders but did not address hair loss, indicating the VDR's role in hair growth.

research Vitamin D Receptor: New Assignments for an Already Busy Receptor

510 citations , August 2006 in “Endocrinology”

This minireview discusses a proposed model of the vitamin D receptor that explains how 1alpha,25(OH)2D3 can mediate both genomic and rapid responses through different ligand shapes and cellular locations, without presenting new research findings.

Deletion of DNA Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D

research Deletion of Deoxyribonucleic Acid Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D

277 citations , July 2002 in “Molecular Endocrinology”

In this study, homozygous VDR null mutant mice exhibited nonfunctional vitamin D receptors, leading to growth abnormalities and revealing the limited physiological importance of vitamin D pathways outside the classical receptor.

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Community Join

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community Is Vitamin D the cause of my baldness or slow regrowth?

in Is this regrowth? 1 upvotes 10 months ago

The conversation discusses hair loss treatments, including oral finasteride, topical minoxidil, and microneedling, and the potential impact of Vitamin D and folic acid deficiencies on hair regrowth. It suggests that while male pattern baldness is the primary cause, addressing vitamin deficiencies may aid in improving regrowth.

community Does drinking coffee have any effect on hairloss?

4 upvotes 5 years ago

Coffee's effect on hair loss is debated, with some suggesting it may exacerbate hair loss due to vasoconstriction, while others believe it could have positive effects. Topical caffeine might be beneficial, but ingesting it could potentially inhibit vitamin D receptors.

community What vitamin deficiencies that cause hair loss

54 upvotes 1 year ago

Vitamin deficiencies, particularly in vitamins A, B, C, D, and minerals like iron, zinc, and copper, can lead to hair loss. Dietary changes, such as eating more nutrient-rich foods, can improve hair health.

community South Korean Red Light Therapy Study

41 upvotes 6 months ago

Korean scientists developed a red light therapy that reduces a hair loss marker by 92%. Users discussed the benefits and drawbacks of natural sunlight versus red light caps for hair health, with some suggesting supplements for vitamin D.

community My Experience and a Discourse on "DUPA"

8 upvotes 2 years ago

The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

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Learn

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learn Vitamin D

vitamin you should probably be taking for general health might also help your hair a little

What is the connection between Vitamin D and hair loss? Vitamin D deficiency may contribute to hair loss by disrupting hair follicle regulation.
Can Vitamin D deficiency trigger excessive hair shedding? Yes, vitamin D deficiency can trigger excessive hair shedding.
Is it safe to take Vitamin D supplements for hair growth? Vitamin D supplements are generally safe but may not significantly improve hair growth.
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learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

learn Overview

learn Calcium D oantothenate

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Clinics

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