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Glossary Skin Aging

natural process where skin loses elasticity and develops wrinkles

Skin aging, also known as aging skin or skin ageing, refers to the natural process where the skin undergoes changes over time, leading to wrinkles, loss of elasticity, and thinning. This process is influenced by intrinsic factors like genetics and hormonal changes, as well as extrinsic factors such as UV exposure, pollution, and lifestyle choices.

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Research

5 / 1000+ results

research Fruit Acid Inhibits UV-Induced Skin Aging via PI3K/Akt and NF-κB Pathway Inhibition

3 citations , January 2025 in “Discovery Medicine”

This study found that glycolic acid treatment reduced oxidative stress and inflammation in UV-induced skin photoaging in rats, promoting collagen recovery and reducing photoaging signs, potentially by inhibiting the PI3K/Akt and NF-κB pathways.

research Multi-Omics Reveals That Hydroxypinacolone Retinoate Alleviates UV-Induced Skin Aging via the p38/MMP9/Collagen Axis

August 2026 in “Clinical Cosmetic and Investigational Dermatology”

This study found that Hydroxypinacolone Retinoate (HPR) may alleviate UV-induced skin photoaging by enhancing collagen synthesis, reducing degradation, and modulating inflammatory and oxidative responses in a dose-dependent manner.

research Editorial: Inflammation, stem cells and wound healing in skin aging

October 2022 in “Frontiers in Cell and Developmental Biology”

Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.

research Aging Skin: A Window to the Body

1 citations , April 2016 in “CRC Press eBooks”

Skin aging reflects overall body aging and can indicate internal health conditions.

Skin Aging in Women: Pathophysiology and Treatment

research Skin Ageing in Women: Pathophysiology and Treatment

September 1999 in “The Journal of The British Menopause Society”

This review discusses how menopause and hormone replacement therapy affect skin aging in women but reports no new clinical findings.

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Community Join

5 / 67 results

community Finasteride and “anti-aging” effects

in Treatment 218 upvotes 1 year ago

Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

community So does oral minoxidil age your skin or not

43 upvotes 2 years ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community [26M] Min 5 month progress, worse skin?

49 upvotes 2 years ago

A user experienced skin irritation and acne while using Minoxidil foam, but after stopping both the foam and a sea salt spray, their skin improved. They plan to try oral Minoxidil, suspecting the sea salt spray, not Minoxidil, was the main cause of their skin issues.

community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 9 months ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.

community Minoxidil actually reduces wrinkles

in Research/Science 209 upvotes 1 year ago

Minoxidil may improve or worsen skin quality, with topical forms causing dryness and wrinkles, possibly due to alcohol content, while oral forms have fewer side effects. Some users consider using tretinoin to mitigate negative effects.

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