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Glossary Type III Collagen

Type III collagen is a fibrillar collagen that plays a crucial role in the structural integrity of various tissues, including skin, blood vessels, and hair follicles. It is particularly relevant to hair biology as it contributes to the extracellular matrix of the dermal papilla, which is essential for hair follicle development and cycling. Distinguishing characteristics of type III collagen include its ability to form reticular fibers, providing support and elasticity, and its presence in tissues undergoing rapid growth or repair, making it significant in the context of hair loss and regeneration.

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PRO-C22 - A Novel Serological Biomarker of Tissue Damage Is Associated with Disease Severity, Disease Activity, and Systemic Inflammation in Patients with Hidradenitis Suppurativa

research 51826 PRO-C22 - A Novel Serological Biomarker of Tissue Damage is Associated with Disease Severity, Disease Activity, and Systemic Inflammation in Patients with Hidradenitis Suppurativa

September 2024 in “Journal of the American Academy of Dermatology”

PRO-C22 can help diagnose and monitor the severity of hidradenitis suppurativa.

research A Novel Marker of Tissue Junctions, Collagen XXII

226 citations , May 2004 in “Journal of Biological Chemistry”

This study identified collagen XXII as a novel extracellular matrix protein specifically present at tissue junctions, where it functions as a cell adhesion ligand for skin epithelial cells and fibroblasts.

Unraveling the Link Between Insulin Resistance and Androgen Excess

research Unravelling the link between insulin resistance and androgen excess

December 2015 in “University of Birmingham Institutional Research Archive (University of Birmingham)”

This study showed that regulation of adipose androgen generation via AKR1C3 may contribute to a cycle of hyperinsulinaemia and lipid accumulation in women with PCOS.

research Human hair keratin hydrogel : fabrication, characterization and application

January 2014

This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.

research The pathogenesis of alopecia areata

January 2015

In this study, researchers found that alopecia areata is linked to immune cell activation against hair follicle autoantigens and is associated with heart changes and cardiac marker alterations in humans and mice.

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