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    Did you mean Intermediate Filaments?
    GlossaryKeratin Intermediate Filaments

    structural proteins in cells providing support and resilience

    Keratin Intermediate Filaments (KIFs) are structural proteins found in epithelial cells, including those in the skin, hair, and nails. They provide mechanical support and resilience, helping cells withstand stress and maintain their shape. KIFs are a type of intermediate filament, which are part of the cytoskeleton, a network that supports cell structure and function.

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      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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      community Anti Fibrosis and Calcification regimen?

      in Question  10 upvotes 7 years ago
      The user experienced no improvement in hair loss with finasteride and minoxidil but had side effects. They plan to add wounding, scalp massage, vitamin K, and taurine supplements to their regimen and seek feedback on these additions.

      community 7 months update - 1 mg fin, topical min

      in Progress Pictures  736 upvotes 1 year ago
      A user's 7-month progress using 1 mg finasteride and topical minoxidil, with no side effects from the finasteride, achieving baby hairs on the hairline and other positive results. Other users have discussed different treatments such as microneedling and supplements, providing advice and encouragement to the poster.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 6 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.