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    Glossary Intermediate Filaments

    structural proteins in cells providing mechanical support and stability

    Intermediate filaments are a type of structural protein found within cells that help maintain their shape and integrity. They are part of the cytoskeleton, which also includes microtubules and actin filaments, and they provide mechanical support to cells, enabling them to withstand stress and strain.

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    1. Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament Genomics · 2007 · 27 citations
    2. Sequence analyses of Type I and Type II chains in human hair and epithelial keratin intermediate filaments: Promiscuous obligate heterodimers, Type II template for molecule formation and a rationale for heterodimer formation Journal of Structural Biology · 2006 · 19 citations
    3. Hair follicle differentiation: expression, structure and evolutionary conservation of the hair type II keratin intermediate filament gene family Development · 1992 · 65 citations
    4. Complete sequence of a hair-like intermediate filament type II keratin gene DNA sequence · 1993 · 15 citations
    5. A Unique Type I Keratin Intermediate Filament Gene Family is Abundantly Expressed in the Inner Root Sheaths of Sheep and Human Hair Follicles Journal of Investigative Dermatology · 2001 · 41 citations
    6. A Novel Mouse Type I Intermediate Filament Gene, Keratin 17n (K17n), Exhibits Preferred Expression in Nail Tissue Journal of Investigative Dermatology · 2004 · 31 citations
    7. Role of human type II hair keratins in intermediate filament bundling in vitro 2015
    8. Three-dimensional modelling of interchain sequence similarities and differences in the coiled-coil segments of keratin intermediate filament heterodimers highlight features important in assembly Journal of Structural Biology · 2007 · 13 citations
    9. Structure and Mechanical Properties of Human Trichocyte Keratin Intermediate Filament Protein Biomacromolecules · 2012 · 51 citations
    10. Structural Stability of Wild Type and Mutated α-Keratin Fragments:  Molecular Dynamics and Free Energy Calculations Biomacromolecules · 2004 · 40 citations
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