287 citations
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March 1999 in “The Plant Journal” This study found that disrupting the microtubule cytoskeleton in Arabidopsis root hairs caused loss of growth directionality and suggested microtubules interact with calcium gradients to regulate apical growth stability.
32 citations
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December 2003 in “Planta” This study found that hypaphorine alters cytoskeletal organization in Eucalyptus globulus root hairs, contributing to reduced root hair elongation by possibly disrupting vesicle delivery needed for growth.
3 citations
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January 2016 In this study, NuMA's microtubule-binding domain was found to be crucial for correct spindle orientation and skin differentiation, with its loss leading to neonatal lethality in mice.
July 2026 in “Nature Communications” This study reports that brief exposure to low intensity and low frequency ultrasound was able to transiently break cellular microtubules and mitigate hair follicle damage, suggesting a potential method to prevent hair loss during chemotherapy with taxanes like paclitaxel.
14 citations
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October 2002 in “Journal of cutaneous pathology” This study found that MAP-2 is intensely expressed in the companion layer of the hair follicle, suggesting its potential importance to follicle integrity and possible involvement in some types of alopecia.