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    Did you mean 11-beta-Hydroxysteroid Dehydrogenase Type 1?
    Glossary11β-Hydroxysteroid Dehydrogenase Type 1

    enzyme converting inactive cortisone to active cortisol

    11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) is an enzyme that converts inactive cortisone into active cortisol, a hormone involved in stress response, metabolism, and immune function. This enzyme is found in various tissues, including the liver and adipose tissue, and plays a role in conditions like obesity, diabetes, and potentially hair loss due to its influence on local cortisol levels.

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      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

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      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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      community 2 months on minoxidil 5% GOOD RESULTS?

      in Progress Pictures 2 years ago
      Asteride into your routine In this conversation, the user Icy-Indication267 was asking when they should start finasteride to treat their hair loss, which had responded well to minoxidil after two months. Other users shared advice on incorporating micro-needling and topical finasteride into their routine for optimal results.

      community Why am I so scared to start fin?

      in Finasteride/Dutasteride  15 upvotes 2 years ago
      User is scared to start finasteride for hair loss due to potential side effects and personal concerns. Another user suggests trying a low dose for 6 months and avoiding online groups to reduce anxiety.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 month ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.