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Glossary Type I Collagen

most abundant protein in skin, bones, and tendons

Type I Collagen is the most abundant collagen in the human body, making up about 90% of the collagen found in skin, bones, tendons, and other connective tissues. It provides structural support and strength, playing a crucial role in wound healing and maintaining the integrity of various tissues.

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Research

5 / 1000+ results

research Promoting effect of type 17 collagen production by chlorogenic acid using PLGA nanoparticles in the human epidermal keratinocyte cell

8 citations , February 2020 in “Journal of Drug Delivery Science and Technology”

This study demonstrated that using PLGA nanoparticles to deliver chlorogenic acid significantly increased type 17 collagen production in human epidermal cells, indicating potential for improved skincare formulations.

research 583 Induction of type 17 collagen decreases ultraviolet b-induced cellular senescence in human htert/ker-ct keratinocytes

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that apocynin restored COL17A1 expression in human keratinocytes and reduced UVB-induced cellular senescence, DNA damage, and cell cycle arrest.

Effects of Collagen Type XVII Alpha 1 on Epidermal Stem Cells in Aging Skin and the MicroRNA Intervention Mechanism

research [Effects of collagen type ⅩⅦ α1 on epidermal stem cells in aging skin and the microRNA intervention mechanism].

September 2022 in “PubMed”

This study found that decreased COL17α1 expression in aging mouse skin is associated with reduced proliferation of epidermal stem cells and may contribute to thinner epidermis and slower wound healing.

Transforming Growth Factor-β, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes

research Transforming Growth Factor-??, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes

16 citations , February 2007 in “Plastic and Reconstructive Surgery”

This study found that keratinocytes show increased expression of the TGF-β system and collagen type I with age, suggesting a heightened profibrotic response during skin differentiation associated with scarring.

research Anti-aging effects of black raspberry extract on cataract, alopecia, skin whitening, and weight loss

10 citations , January 2018 in “Functional Foods in Health and Disease”

This study found that berry extracts, especially black raspberry extract, may have anti-aging effects due to their high antioxidant activities.

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Community Join

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community 17 month updateBefore & after pic.

in Progress Pictures 540 upvotes 1 year ago

The conversation discusses a user's impressive hair regrowth progress over 17 months using a topical minoxidil and finasteride spray from HIMS, with suggestions to add microneedling for better results. Some users express skepticism about the authenticity of the results, while others inquire about side effects and application methods.

community Started balding at 17 im 19 now 1 year on min started fin today Best its looked in years

in Progress Pictures 75 upvotes 8 months ago

A 19-year-old shared progress on hair regrowth after using minoxidil for a year and starting finasteride. Users discussed the effectiveness and side effects of these treatments, with some expressing concerns about potential side effects and others sharing positive experiences.

community 1 year on fin. No results. I give up.

in Finasteride/Dutasteride 43 upvotes 3 years ago

A user who has been taking finasteride, minoxidil, and microneedling for one year with no results, and the replies discuss other treatments, including dutasteride, which is feared due to potential side effects.

community 17M - beat the norwood reaper in 4 months. Am I a hyper responder? Can I maintain for a year until I can start fin?

in Progress Pictures 725 upvotes 1 year ago

A 17-year-old improved his hairline using minoxidil and derma stamping, planning to start finasteride at 18. He received advice on dosing and potential side effects to maintain results.

community Reversing 8 years of hair loss. Dut is freaking magic!

4082 upvotes 1 year ago

A user successfully reversed hair loss over 17 months using 0.5mg dutasteride and 5mg oral minoxidil daily, noting significant improvement without a transplant. Minor side effects like headaches and testicular discomfort were reported but resolved quickly.

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Learn

4 / 801 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn collagen

learn nonspecific group of soluble collagens

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Clinics

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Experts

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