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    Glossary Type I Collagen

    most abundant protein in skin, bones, and tendons

    Type I Collagen is the most abundant collagen in the human body, making up about 90% of the collagen found in skin, bones, tendons, and other connective tissues. It provides structural support and strength, playing a crucial role in wound healing and maintaining the integrity of various tissues.

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    Research 30 of 1000+

    1. Promoting effect of type 17 collagen production by chlorogenic acid using PLGA nanoparticles in the human epidermal keratinocyte cell Journal of Drug Delivery Science and Technology · 2020 · 8 citations
    2. 583 Induction of type 17 collagen decreases ultraviolet b-induced cellular senescence in human htert/ker-ct keratinocytes 2022
    3. [Effects of collagen type ⅩⅦ α1 on epidermal stem cells in aging skin and the microRNA intervention mechanism]. PubMed · 2022
    4. Transforming Growth Factor-??, Smad, and Collagen Expression Patterns in Fetal and Adult Keratinocytes Plastic and Reconstructive Surgery · 2007 · 16 citations
    5. Anti-aging effects of black raspberry extract on cataract, alopecia, skin whitening, and weight loss Functional Foods in Health and Disease · 2018 · 10 citations
    6. 520 The protective effects of Apocynin against ultraviolet B-induced cellular senescence in human keratinocytes Journal of Investigative Dermatology · 2022
    7. <i>Ishige sinicola</i> extract stimulates osteoblast proliferation and differentiation via the bone morphogenetic protein 2/runt-related gene 2 signalling pathway Zeitschrift für Naturforschung C · 2019 · 4 citations
    8. Docosahexaenoic acid slows inflammation resolution and impairs the quality of healed skin tissue Clinical Science · 2019 · 8 citations
    9. Read-Through for Nonsense Mutations in Type XVII Collagen‒Deficient Junctional Epidermolysis Bullosa 2022 · 5 citations
    10. Bacitracin-Loaded Type I Collagen/Bacterial Cellulose Dressing for the Repair of Infected Wounds Journal of Functional Biomaterials · 2026
    11. Life before and beyond blistering: The role of collagen XVII in epidermal physiology Experimental Dermatology · 2018 · 63 citations
    12. Senotherapeutic Potential of Araliadiol in Senescent Human Dermal Fibroblasts: An In Vitro Study Using Three Senescence Models Pharmaceutics · 2025
    13. SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin Journal of Investigative Dermatology · 2018 · 225 citations
    14. Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis Journal of Dermatological Science · 2017 · 8 citations
    15. Stabilization of Hemidesmosomal Proteins: A Possible Key Contributor to Wnt/β-Catenin Pathway Action in the Skin Journal of Investigative Dermatology · 2021
    16. The distributions of type IV collagen .ALPHA. chains in basement membranes of human epidermis and skin appendages Archives of Histology and Cytology · 2007 · 36 citations
    17. Synergistic Effects of Fractional CO <sub>2</sub> Laser and Recombinant Humanized Type III Collagen (rhCol III) in Atrophic Acne Scar Treatment: Activation of MAPK Pathway and Enhanced Collagen Remodeling Dermatologic Therapy · 2025
    18. Recombinant Type XVII Collagen Promotes Hair Growth by Activating the Wnt/β-Catenin and SHH/GLI Signaling Pathways Cosmetics · 2025
    19. Type XVII collagen coordinates proliferation in the interfollicular epidermis eLife · 2017 · 124 citations
    20. Basement Membrane Zone Remodeling During Appendageal Development in Human Fetal Skin. The Absence of Type VII Collagen is Associated with Gelatinase-A (MMP2) Activity Journal of Investigative Dermatology · 2000 · 42 citations
    21. Type 1 Diabetes Mellitus and Autoimmune Diseases: A Critical Review of the Association and the Application of Personalized Medicine Journal of Personalized Medicine · 2023 · 12 citations
    22. Accelerative action of topical piperonylic acid on mice full thickness wound by modulating inflammation and collagen deposition PLoS ONE · 2021 · 3 citations
    23. Histological and molecular restoration of type VII collagen in Recessive dystrophic epidermolysis bullosa mouse skin by topical injection of keratinocyte-like cells differentiated from human adipose-derived mesenchymal stromal cells Journal of Dermatological Science · 2024 · 1 citations
    24. Silk fibroin hydrogel with recombinant silk fibroin/NT3 protein enhances wound healing by promoting Type III collagen synthesis and hair follicle regeneration in skin injury Materials Today Bio · 2025
    25. Identification of a human type XVII collagen fragment with high capacity for maintaining skin health Synthetic and systems biotechnology · 2024
    26. Biological Macromolecule Hydrogel Based on Recombinant Type I Collagen/Chitosan Scaffold to Accelerate Full-Thickness Healing of Skin Wounds Polymers · 2023 · 12 citations
    27. Plasma-Polymerised Antibacterial Coating of Ovine Tendon Collagen Type I (OTC) Crosslinked with Genipin (GNP) and Dehydrothermal-Crosslinked (DHT) as a Cutaneous Substitute for Wound Healing Materials · 2023 · 6 citations
    28. Borate-modified recombinant type XVII collagen microneedles loaded with IGF-1 for the treatment of androgenetic alopecia International Journal of Biological Macromolecules · 2025
    29. Comparison of mitochondrial transplantation by using a stamp-type multineedle injector and platelet-rich plasma therapy for hair aging in naturally aging mice Biomedicine & Pharmacotherapy · 2020 · 9 citations
    30. Collagen Hydrolysate from the Scales of Mozambique Tilapia (Oreochromis mossambicus) Improve Hair and Skin Health by Alleviating Oxidative Stress and Inflammation and Promoting Hair Growth and Extracellular Matrix Factors Marine drugs · 2023 · 2 citations