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GlossaryTUNEL assay

detects DNA fragmentation in cells undergoing apoptosis

The TUNEL assay, or Terminal deoxynucleotidyl transferase dUTP nick end labeling, is a laboratory technique used to detect DNA fragmentation resulting from apoptotic signaling. It works by labeling the ends of broken DNA strands, allowing researchers to identify and quantify cells undergoing programmed cell death, which can be important in studies of diseases like cancer or conditions affecting hair follicles, such as alopecia.

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research A Primer for Studying Cell Cycle Dynamics of the Human Hair Follicle

38 citations, April 2016 in “Experimental Dermatology”

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

research YAP And TAZ Are Essential For Basal And Squamous Cell Carcinoma Initiation

76 citations, June 2018 in “EMBO Reports”

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

research Folliculin Deficient Renal Cancer Cells Show Higher Radiosensitivity Through Autophagic Cell Death

4 citations, January 2014 in “The Journal of urology/The journal of urology”

Kidney cancer cells without folliculin are more sensitive to radiation due to increased self-eating cell death.

Botulinum Toxin Type A Alleviates Androgenetic Alopecia by Inhibiting Apoptosis of Dermal Papilla Cells via Targeting Circ_0135062/Mir-506-3p/Bax Axis

research Botulinum Toxin Type A Alleviates Androgenetic Alopecia by Inhibiting Apoptosis of Dermal Papilla Cells via Targeting Circ_0135062/Mir-506-3p/Bax Axis

January 2024 in “Aesthetic Plastic Surgery”

Botox can help prevent hair loss by blocking cell death in scalp cells.

Induction of Hair Growth in Hair Follicle Cells and Organ Cultures Upon Treatment with 30 kHz Frequency Inaudible Sound via Cell Proliferation and Antiapoptotic Effects

research Induction of Hair Growth in Hair Follicle Cells and Organ Cultures Upon Treatment with 30 kHz Frequency Inaudible Sound via Cell Proliferation and Antiapoptotic Effects

January 2022 in “Biomedical Reports”

Inaudible sound at 30 kHz can boost hair growth and decrease hair loss by promoting cell growth and reducing cell death in hair follicles.

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community 9 months fin+microneedling/2 years min, looks like there’s a light at the end of the tunnel

in Progress Pictures 100 upvotes 1 year ago

User shared 9-month progress with finasteride and microneedling, and 2-year progress with minoxidil for hair loss. Others asked about microneedling tools, routine, and suggested micro fibers for improvement.

community Exosome Hair Rejuvenation (2nd Month UPDATE!)

in Progress Pictures 3 upvotes 2 years ago

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

community Why balding gets worse in every generation?

in Chat 81 upvotes 8 months ago

Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

community I regrew my hairline in 2 years. Never give up hope. No transplant involved either.

in Progress Pictures 1079 upvotes 8 months ago

A user shared their 2-year hair regrowth journey using finasteride, ketoconazole shampoo, and a diet change, without a hair transplant. Despite skepticism from others, the user insists the results are natural and encourages consistency and dietary adjustments.

community Q1 2024 is done. And kintor is completely silent about GT20029.

in Research/Science 28 upvotes 11 months ago

The conversation discusses the lack of updates on GT20029 for hair loss treatment, with some users noting recent reports indicating ongoing data collection. There are mentions of other treatments like Pyrilutamide and Minoxidil.

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