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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Caffeine

      the stimulant you know and love can be used topically to stimulate hair

      learn GT20029

      research compound made to degrade androgen receptors in scalp

    Research

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      community Trialing the probiotics BB536, PTA 6475 so you don’t have to

      in Research/Science  75 upvotes 4 months ago
      Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.
      Sudden Triangular Thinning Patch

      community Sudden Triangular Thinning Patch

      in General  157 upvotes 2 months ago
      A 31-year-old has been using finasteride, dutasteride, and oral minoxidil for hair loss. They noticed a sudden triangular thinning patch on their scalp and are seeking advice, questioning if it could be medication-related.