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Research

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research Efficacy of topical nanoemulsion (NB-002) for the treatment of distal subungual onychomycosis: A randomized, double-blind, vehicle-controlled trial

February 2010 in “Journal of The American Academy of Dermatology”

NB-002 is a promising new topical treatment for fungal nail infections, showing better results than a non-medicated option.

research Topical delivery of nanoemulsions for skin cancer treatment

34 citations , November 2023 in “Applied Materials Today”

This review discusses the potential of topical nanoemulsions to transform skin cancer treatment by improving drug delivery and minimizing side effects, highlighting their advantages like enhanced skin permeation and controlled release, despite existing challenges.

research Effect of topical nanoemulsion of minoxidil on animal hair growth: an in vivo study

June 2026 in “Journal of Materials Science Materials in Medicine”

This study explored nanoemulsions of minoxidil, revealing that a 5% minoxidil nanoemulsion improved hair growth and follicle count in animal studies compared to commercial minoxidil solutions, even without significant differences in permeation rates.

research Colistin adorned topical nanoemulsion gel formulation for enhanced anti-microbial activity

1 citations , September 2025 in “Scientific Reports”

This study reported that a colistin sulfate-loaded nanoemulgel showed improved antimicrobial activity and skin permeability compared to a CS solution, suggesting a potential new approach for treating severe infections caused by multidrug-resistant bacteria.

research Essential oils-based nanoemulsion formulation boosts hair growth in C57BL/6 mice as compared to minoxidil 2%

November 2025 in “Discover Pharmaceutical Sciences”

In this study, a nanoemulsion containing lavender, peppermint, and rosemary essential oils was developed and shown to promote hair growth in mice at a rate comparable to 2% topical minoxidil, suggesting a promising natural alternative due to its antioxidant and anti-inflammatory effects.

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Community Join

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community Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting

4 upvotes 1 year ago

Minoxidil can be effectively delivered through nanoemulsions containing eucalyptol or oleic acid, enhancing its diffusivity and targeting hair follicles. This contradicts the advice against mixing minoxidil with oils in topical formulations.

community How to deal with mechanically induced shedding

4 upvotes 11 months ago

Minoxidil can cause scalp dryness and flaking, leading to hair shedding when exfoliating. Alternatives like oral Minoxidil, finasteride, and ketoconazole shampoo are suggested to manage these issues.

community Topical minoxidil routine and shampooing frequency

4 upvotes 4 days ago

The user applies 10% minoxidil nightly, takes 1mg finasteride, multivitamins, and a hair growth serum, and is concerned about over-washing hair with dermatologist-recommended shampoo. It is suggested to shampoo every other day and rinse with water on alternate days unless otherwise advised by a dermatologist.

community Topical min 13 months and oral fin 6 months, progress

11 upvotes 5 days ago

The user has been using topical minoxidil for 13 months and oral finasteride for 6 months to address hair loss after a hair transplant. They plan to switch to oral minoxidil for better results and occasionally use topical minoxidil and microneedling.

community F23 does Topical Min work on vellus hairs?

in Female 72 upvotes 6 days ago

Topical minoxidil 5% may help turn vellus hairs into normal-looking hairs, but results can vary, especially on the temples. The user stopped testosterone injections and finasteride, which may have affected hair recovery.

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Learn

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learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. In studies, topical finasteride gave much lower blood levels of the drug than tablets but still lowered blood DHT, and whether it causes fewer side effects has not been established. There is no FDA-approved topical finasteride, and the FDA warned about compounded versions in April 2025.

learn Cetirizine

Is topical cetirizine effective for androgenetic alopecia in women? Topical cetirizine is not an approved product and its use for female-pattern hair loss is off-label. The evidence is one small pilot study in mixed-sex patients and one randomized trial in 66 women where cetirizine was added to minoxidil; it is unproven on its own.

learn Glycerin

Does topical glycerin have any effect on hair thickness or follicle function? Topical glycerin mainly hydrates the hair and scalp; no study has shown that it increases hair thickness or changes follicle function.

learn Valproic acid

How is valproic acid being explored differently in topical hair products compared to its traditional oral medical use? Topical valproic acid is being studied for local effects on the hair follicle rather than the whole-body effects of the oral drug. The human evidence is one small randomized 24-week trial of an 8.3% spray; no topical valproate product is approved for hair loss.

learn Vitamin B12

Can topical products containing Vitamin B12 improve scalp health and hair growth? Topical Vitamin B12 may not significantly improve hair growth unless there's a deficiency.

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