37 citations
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November 1995 in “Journal of Investigative Dermatology”
Topicalfinasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.
This conversation is about a user who has been using topicalfinasteride and minoxidil for 6 months and has seen great results, with some side effects. Others have shared their progress and advice on how to further maximize the effectiveness of the treatments.
Topicalfinasteride as a potential alternative to oral finasteride for reducing DHT levels on the scalp with fewer side effects, and other hair loss treatments such as minoxidil.
Topicalfinasteride can effectively reduce scalp DHT by targeting local enzymes, despite less systemic impact compared to oral forms. Combining oral dutasteride with topicalfinasteride and minoxidil may enhance hair loss prevention, though evidence of its effectiveness is limited.
TopicalFinasteride is most effective at 0.1-0.25%, and Minoxidil at 5%. Tretinoin is optional, and additional ingredients like biotin, caffeine, and saw palmetto are recommended.
Topicalfinasteride is currently more effective than pyrilutamide for hair loss. Combining treatments like topicalfinasteride and pyrilutamide may enhance results due to different mechanisms.