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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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Tracking 1 products like 132 URODART 0.5MG 28 capsule from by companies like Minoxidil Express. View product »Learn
5 / 14 resultslearn Platelet-Rich Plasma
growth factors taken from your blood and injected into your scalp to stimulate hair
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chemical that might completely regrow follicles from hair transplant extractions
learn GHK-Cu
a copper peptide showing promise in both regrowth and reversing gray hair
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Research
5 / 1000+ resultsresearch Effect of Citral on Experimentally Induced Comedones
1% citral is more effective for treating comedone acne than salicylic acid.
research Skin Cell-Derived Extracellular Vesicles: A Promising Therapeutic Strategy for Cutaneous Injury
Skin cell-derived vesicles can help heal skin injuries effectively.
research Hyperplasia of the Subcutaneous Adipose Tissue Is the Primary Histopathologic Abnormality in Lipedematous Scalp
Lipedematous scalp is mainly caused by an increase in fat tissue under the skin and is different from lipedematous alopecia.
research Sustained Release of EGF/bFGF Growth Factors by Mussel-Inspired Core-Shell Nanofibers with Hemostatic and Anti-Inflammatory Effects for Promoting Wound Healing
The new nanofiber improves wound healing by releasing growth factors, reducing inflammation, and helping skin regeneration.
research Acute Sensitivity of the Oral Mucosa to Oncogenic K-ras
Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.
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community FCE 28260: A Forgotten 5α-Reductase Inhibitor
by
nkrata
in Research
330 upvotes
1 year ago FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community How To Switch from Finasteride to Dutasteride (according to literature)
Switching from finasteride to dutasteride for hair loss treatment. Dutasteride is suggested as a more effective alternative.
community How to Switch from Finasteride to Dutasteride according to literature.
Switching from finasteride to dutasteride involves gradually increasing dutasteride while decreasing finasteride. Studies show dutasteride 0.5 mg daily can improve hair density in men unresponsive to finasteride.
community Hair theory Scar tissue and Verteporfin
A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.
community New and Interesting HairLoss Studies/Papers/Reviews
Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.