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GlossaryT helper 17 cells (Th17 cells)

specialized immune cells involved in inflammation and autoimmune responses

T helper 17 cells, often abbreviated as Th17 cells, are a subset of T cells, which are a type of white blood cell crucial for the immune system. Th17 cells play a key role in defending the body against bacterial and fungal infections by producing a specific set of signaling molecules called cytokines, particularly interleukin-17 (IL-17). They are also involved in inflammatory responses and have been implicated in various autoimmune diseases, where the immune system mistakenly attacks the body's own tissues.

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Clinical and Immunological Impact of Booster Immunization With Recombinant mRNA Vaccines for SARS-CoV-2 in Patients With Pemphigus and Bullous Pemphigoid

research Clinical and Immunological Impact of Booster Immunization With Recombinant mRNA Vaccines for SARS-CoV-2 in Patients With Pemphigus and Bullous Pemphigoid

April 2023 in “Journal of Investigative Dermatology”

Booster shots of mRNA vaccines for COVID-19 increased protective antibodies without worsening autoimmune skin conditions in patients.

research Overexpression of Hypoxia-Inducible Factor-1α in Hidradenitis Suppurativa: The Link Between Deviated Immunity and Metabolism

5 citations, March 2023 in “Archives of dermatological research”

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

research Extraskeletal Actions of Vitamin D

119 citations, July 2016 in “Annals of the New York Academy of Sciences”

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

research Treatment of Crohn's Disease and Concomitant Alopecia Areata With Tofacitinib

2 citations, November 2021 in “ACG Case Reports Journal”

Tofacitinib successfully treated hair loss in a Crohn's disease patient who previously used adalimumab.

research Randomized Split-Side Study Comparing Efficacy of Botulinum Toxin Type A Versus 0.9% Sodium Chloride in Scalp Psoriasis

January 2018

Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.

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