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research Evaluation of the 5α-Reductase Inhibitor Finasteride on Reproduction and Gonadal Development in Medaka, Oryzias Latipes
Finasteride negatively affects fish reproduction and gonadal development.
research Chronic Exposures to the Herbicide Atrazine and the Pharmaceutical Finasteride Disrupt Sex Steroid and Thyroid Hormone Signaling and Gonadal Development in Frogs
Atrazine and finasteride disrupt hormone signaling and affect frog development.
research Expression Profiles of Reproduction and Thyroid Hormone Related Transcripts in the Brains of Chemically Induced Intersex Frogs
Intersex frogs have different brain gene activity related to sex and thyroid hormones.
research The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog Silurana Tropicalis
Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
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5 / 178 resultscommunity Mechanism of action of alfatradiol (17 alpha estradiol)
The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.
community Tressless Pyrilutamide data analytics – Frustrated with lack of data, so I did something about it!
This user has conducted data scraping of 365 Reddit posts on the hairloss drug Pyrilutamide over the last year to analyse efficacy and side effects. The findings, which are available in a 19 page report with graphs, suggest that 22% of Pyrilutamide users experience positive results while 63% experience symptoms. A larger analytics project is proposed for other drugs with enough demand.
community Guys who used fin and had to stop, what were your reasons?
Somitomere used finasteride for two years, experienced mental side effects, and stopped. They are now waiting for a new treatment like Breezula.
community Finasteride has not only helped my hairline but also the thickness of my hair and has helped it grow a lot in general over the last 6 months. Thoughts?
Finasteride helping to improve the user's hairline, thickness, and growth over the last 6 months. Other users offered their support and encouragement.
community Is this true? Is long term taking fin harmful to the liver?
The conversation discusses whether long-term use of finasteride (Fin) is harmful to the liver, with various opinions on side effects and comparisons to other substances. Specific treatments mentioned include finasteride, minoxidil (Min), and RU58841 (RU).