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Glossary Terminal Hair

thick, coarse, pigmented hair found on the scalp and body

Terminal hair refers to the thick, coarse, and pigmented hair that develops during puberty and is found on various parts of the body, such as the scalp, eyebrows, eyelashes, and, in adults, the armpits and pubic region. Unlike vellus hair, which is fine and light, terminal hair is more robust and plays a role in providing protection and insulation.

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Research

5 / 1000+ results

research Pattern hair loss: Assessment of microinflammation in miniaturized and terminal hair follicles through horizontal histologic sections

11 citations , April 2020 in “Journal of The American Academy of Dermatology”

This commentary reviews the evidence for microinflammation's role in pattern hair loss and suggests that further studies with age- and sex-matched controls are needed to substantiate the findings.

research Hair regrowth in male and female pattern hair loss does not involve the conversion of vellus hair to terminal hair

14 citations , January 2016 in “Experimental Dermatology”

This analysis concluded that hair regrowth in male and female pattern hair loss treatments did not involve converting vellus hairs into terminal hairs, suggesting a reactivation of dormant non-vellus follicles instead.

research Viable terminal scalp hair follicles constitute a necessary and sufficient biological end‐organ that conditions clinical efficacy of finasteride in males with male pattern hair loss without implying reversal of miniaturized follicles

6 citations , June 2019 in “Skin Research and Technology”

In this study, finasteride treatment for two years did not significantly reverse miniaturized hair follicles in men with male pattern hair loss, challenging the "reversal hypothesis" as 79 out of 113 miniaturized hairs remained unchanged.

research Maintenance of optimised hair growth from viable terminal scalp hair follicles at baseline with oral finasteride in male pattern hair loss and first evidence of a “drug dependency” and a post-finasteride “rebound effect”.

4 citations , May 2019 in “Skin Research and Technology”

This study found that male pattern hair loss worsened significantly after stopping finasteride, revealing a "rebound effect" where terminal hair transformed into miniaturized hair over 30 months off the drug.

research Efficacy and Safety of a Low-level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-controlled, Double-blind Study

147 citations , January 2014 in “American Journal of Clinical Dermatology”

This study found that low-level laser treatment with the HairMax Lasercomb significantly increased terminal hair density in both men and women with pattern hair loss, with no serious adverse events reported.

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Community Join

5 / 562 results

community Turning vellus hairs into terminal hair

in Research/Science 12 upvotes 1 year ago

People are discussing hair loss treatments, including minoxidil, finasteride, and RU58841, to turn vellus hairs into terminal hairs. Some users also mention using antibiotics, oral minoxidil, dutasteride, DHT blockers, biotin, and natural remedies like onion juice and seeds to improve hair growth.

community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

7 upvotes 5 months ago

AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

community 2-Month Progress on Hair Loss Treatment: Is It Working ?

7 upvotes 4 months ago

The user is using Minoxidil, Finasteride, a dermaroller, vitamin D, and anti-hair loss shampoo for hair loss treatment. There is some vellus regrowth, and shedding may indicate future terminal hair growth.

community 52 year old norwood 6 vellus to terminal, 5 months progress

12 upvotes 2 months ago

A 52-year-old with Norwood 6 hair loss shows progress after 5 months using topical dutasteride, LLLT, copper peptides, Ulo serum, Minoxidil, cetirizine, and microneedling. Native hair is regrowing from vellus to terminal, with increased density in previously bald areas.

community Why don't Minoxidil regenerated hairs become terminal on the head?

in Minoxidil 101 upvotes 1 year ago

Minoxidil helps hair growth by increasing blood flow and prolonging the growth phase, but it doesn't address the root cause of hair loss, such as DHT sensitivity. Finasteride can help maintain some gains by blocking DHT, but stopping Minoxidil often leads to hair loss because the new hairs are dependent on it.

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Learn

9 / 801 results

learn Clascoterone

How long does it take for clascoterone to show results on hair growth? Clascoterone is not approved for hair loss; it is investigational. In the trials reported so far, application was twice daily and increases in terminal hair count were reported at around 6 months, with more sustained change reported between 6 and 12 months.

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Thymosin Beta 4

learn Stem Cell Factor

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.
How does TDM-105795 differ from more established hair loss ingredients when included in experimental or emerging treatments? TDM-105795 targets thyroid hormone receptors, differing from established treatments like minoxidil and finasteride.

learn GT20029

What is GT20029 and how does it work as a topical anti-androgen for hair loss? GT20029 is a topical anti-androgen that degrades androgen receptors to combat hair loss.

learn Hair Transplant

What is male pattern baldness? Male pattern baldness is a genetic condition causing hair loss in men, starting with a receding hairline.

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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