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      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

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      community Binding affinity of pyrilutamide!

      in Update  169 upvotes 3 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community What to do if fin is still not working after 2.5 years

      in Finasteride/Dutasteride  22 upvotes 2 weeks ago
      The user is experiencing increased hair loss despite using finasteride and oral minoxidil and is hesitant to switch to dutasteride due to side effects and family planning concerns. Alternatives suggested include dutasteride, microneedling, and addressing stress or nutrient deficiencies.

      community Switch from fin to dut and its worse

      in Finasteride/Dutasteride  2 upvotes 1 month ago
      Switching from finasteride to dutasteride can worsen hair loss for some men due to increased testosterone levels. Topical treatments like RU58841 and Pyrilutamide are suggested to counteract these effects, but individual responses vary.