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Glossary Dermal Delivery

method of administering substances through skin for local or systemic effects

Dermal delivery refers to the method of administering active ingredients or medications through the skin. This approach is used to target local conditions or to achieve systemic effects by allowing the substances to penetrate the skin layers and enter the bloodstream. It is commonly used in treatments for skin conditions, pain management, and hormone replacement therapy.

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Research

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research Liposomal systems as drug delivery vehicles for dermal and transdermal applications

151 citations , July 2011 in “Archives of Dermatological Research”

This review discusses various strategies to enhance drug delivery through the skin barrier, highlighting liposomes as promising carriers for increased dermal concentrations in topical therapies, but reports no new research results.

research Liposomes and niosomes as potential carriers for dermal delivery of minoxidil

85 citations , January 2007 in “Journal of Drug Targeting”

This study found that liposomal formulations improved minoxidil delivery to skin layers compared to niosomes and a control solution, suggesting enhanced potential for topical hair loss treatment.

research Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin

64 citations , April 2005 in “Journal of Investigative Dermatology”

This study observed that topical oligonucleotide penetration in mouse skin involves a follicular route, suggesting potential suitability for targeting hair follicle-related structures.

research Nanocrystals of medium soluble actives—Novel concept for improved dermal delivery and production strategy

61 citations , May 2014 in “International journal of pharmaceutics”

This research describes a process for producing caffeine nanocrystals, which may enhance skin penetration by accumulating in hair follicles and maintaining stability for two months, paving the way for in vivo testing.

research Nanoethosomes for Dermal Delivery of Lidocaine

30 citations , November 2015 in “Advanced Pharmaceutical Bulletin”

This study found that nanoethosomes containing Lidocaine showed effective skin penetration, suggesting they may be a suitable carrier for topical anesthetic delivery.

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Community Join

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community Targeted Follicular Finasteride Delivery: A Low-Systemic Strategy

15 upvotes 5 months ago

A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.

community What derma rollers/stamps/pens do you use?

in Microneedling 10 upvotes 2 years ago

The conversation is about adding dermarolling to a hair loss treatment routine. The user seeks recommendations for dermarollers, stamps, or pens, emphasizing the importance of quality and proper cleaning.

community Why is my dermatologist strictly against derma stamping/derma rolling?

in Microneedling 27 upvotes 1 year ago

Dermatologists often advise against at-home microneedling due to risks of scarring, infection, and improper technique. Professional guidance is recommended for safe and effective use, with some users reporting positive results when done correctly.

community [M37] 8 months progress with mostly derma rolling and scalp massaging

617 upvotes 1 year ago

A 37-year-old male stopped using finasteride and minoxidil due to side effects and switched to derma rolling, scalp massaging, and Revita shampoo, resulting in thicker, healthier hair with new growth. Users discuss the effectiveness of mechanical scalp stimulation, with some sharing similar positive experiences and others expressing skepticism.

community My derm said they came up with a new serum that is better then fin? What’s y’all’s thoughts

8 months ago

A new serum claims to enhance hair regrowth by amplifying oxygen delivery, improving the effectiveness of treatments like exosomes and peptides. Users are skeptical, questioning its efficacy compared to established treatments like Minoxidil and Finasteride.

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Learn

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learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Vascular Endothelial Growth Factor

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Thymosin Beta 4

learn sh-Polypeptide-7

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